Purified anti-FMRP Antibody, FMRP, O91D10,BioLegend,859001
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
WB -Quality tested
Platform ID
BAB386448882
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-FMRP Antibody, FMRP, O91D10
Cat. No.859001
HostMouse
RRIDAB_2801227 (BioLegend Cat. No. 859001)AB_2801228 (BioLegend Cat. No. 859002)
IsotypeMouse IgG2b, κ
ReactivityHuman, Mouse, Rat
ApplicationWB -Quality tested
ClonalityMonoclonal
Clone NumberO91D10
Concentration0.5 mg/ml
TargetFMRP
ImmunogenHuman recombinant protein fragment: amino acids 36-279
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
Fragile X mental retardation protein 1 (FMRP) is an RNA binding protein important for normal cognitive development. In fragile X syndrome, abnormal expansion of CGG trinucleotide repeats in FMR1, the gene that encodes FMRP, leads to methylation and silencing of this gene. Altered FMPR expression levels leads to severe learning deficits or mental retardation.
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