Purified anti-GDF3 Antibody, GDF3, A21102G,BioLegend,672951

For use in immunohistochemistry on formalin-fixed paraffin-embedded tissue (IHC-P), it is recommended to perform antigen retrieval using Citrate Buffer, 10X (Cat. No. 420902) or Tris-EDTA pH 9.0 Antigen Retrieval Buffer (10X) (Cat. No. 422704).This product is not recommended for use in Western Blot (WB), immunocytochemistry (ICC) or intracellular flow cytometry (ICFC).

Host

Mouse

Reactivity

Human

Application

IHC-P - Quality tested

Platform ID

BAB553391240

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-GDF3 Antibody, GDF3, A21102G
Cat. No.672951
HostMouse
RRIDAB_3699090 (BioLegend Cat. No. 672951)AB_3699090 (BioLegend Cat. No. 672952)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationIHC-P - Quality tested
ClonalityMonoclonal
Clone NumberA21102G
Concentration0.5 mg/mL
TargetGDF3
ImmunogenRecombinant fragment of human GDF3
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

GDF3 (Growth/Differentiation Factor 3) is a member of the transforming growth factor-beta (TGF-β) superfamily, and is involved in regulating stem cell differentiation, tissue patterning, and embryonic development. GDF3 is particularly important in the development of the early embryo, influencing mesoderm and ectoderm formation, and left-right axis patterning. In stem cells GDF3 has been shown to modulate pluripotency, with its expression being critical for maintaining the undifferentiated state. GDF3 also interacts with other signaling pathways, including those of BMPs (bone morphogenetic proteins), to fine-tune cellular processes such as bone formation. In adults, GDF3 is involved in wound healing, the inflammatory response, and skeletal muscle remodeling.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.