Purified anti-GlyT2 (SLC6A5) Antibody, GlyT2, A18174E,BioLegend,870802
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
WB -Quality testedICC- Verified
Platform ID
BAB114023387
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-GlyT2 (SLC6A5) Antibody, GlyT2, A18174E
Cat. No.870802
HostMouse
RRIDAB_2820198 (BioLegend Cat. No. 870801)AB_2820199 (BioLegend Cat. No. 870802)
IsotypeMouse IgG2a, κ
ReactivityHuman, Mouse, Rat
ApplicationWB -Quality testedICC- Verified
ClonalityMonoclonal
Clone NumberA18174E
Concentration0.5 mg/mL
TargetGlyT2
ImmunogenSynthetic peptide corresponding to a.a. 182-199 of mouse SLC6A5
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
Glycine transporter 2 (GlyT2) protein is encoded by the SLC6A5 gene. It is one of the major glycine transporters that is expressed predominantly in the brain stem and spinal cord, and is frequently used as cellular marker for glycinergic neurons in the central nervous system. Mutations in the SLC6A5 gene have been clinically linked to hyperekplexia 3, which has been thought to be caused by disruption of inhibitory neuronal transmission.
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