Purified anti-IDO1 Antibody anti-IDO1 - W16073A,BioLegend,695002

Host

Rat

Reactivity

Human

Application

WB - Quality testedSB - Community verified

Platform ID

BAB703741566

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePurified anti-IDO1 Antibody anti-IDO1 - W16073A
Cat. No.695002
HostRat
RRIDAB_2650744 (BioLegend Cat. No. 695001)AB_2650745 (BioLegend Cat. No. 695002)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationWB - Quality testedSB - Community verified
ClonalityMonoclonal
Clone NumberW16073A
Concentration0.5 mg/ml
TargetIDO1
ImmunogenHuman IDO1 recombinant protein (154-403 a.a.) expressed inE. coli.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

IDO1 is also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. IDO1 is a ubiquitously expressed cytoplasmic protein with a predicted molecular weight of approximately 45 kD. It is one of the best known IFN-γ inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta.

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