Purified anti-MAPK14 Antibody, MAPK14, 5A1-C5-F11,BioLegend,602651

For ICC, we recommend 4% PFA fixation followed by permeabilization with ice cold methanol. We do not recommend 4% PFA fixation followed by permeabilization with 0.5% Triton-X, or fixation/permeabilization with ice cold methanol alone.

Host

Mouse

Reactivity

Human, Mouse

Application

WB - Quality testedIHC-P, ICC - Verified

Platform ID

BAB315782818

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-MAPK14 Antibody, MAPK14, 5A1-C5-F11
Cat. No.602651
HostMouse
RRIDAB_2910477 (BioLegend Cat. No. 602651)AB_2910477 (BioLegend Cat. No. 602652)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse
ApplicationWB - Quality testedIHC-P, ICC - Verified
ClonalityMonoclonal
Clone Number5A1-C5-F11
Concentration0.5 mg/mL
TargetMAPK14
ImmunogenRecombinant human MAPK14 protein fragments
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

MAPK14 is a member of the p38 MAPK family of serine/threonine-specific kinases. MAPK14 plays a critical role in signal transduction, and upon activation, modulates the activity of diverse signaling families, such as the TNF, TGF, and EGFR pathways, and regulates diverse behaviors including inflammation, stress response, cell cycle, apoptosis, transcription and translation. MAPK14 is important for organogenesis, participating in the development of the heart and blood vessels.

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