Purified anti-MECP2 Antibody anti-MECP2 - N227/21,BioLegend,814001
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
IHC-P -Quality testedICC -Verified
Platform ID
BAB508412840
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-MECP2 Antibody anti-MECP2 - N227/21
Cat. No.814001
HostMouse
RRIDAB_2564780 (BioLegend Cat. No. 814001)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse, Rat
ApplicationIHC-P -Quality testedICC -Verified
ClonalityMonoclonal
Clone NumberN227/21
Concentration1 mg/mL
TargetMECP2
ImmunogenThis monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 157-169 (FTVTG[dimethyl-R]GSPSRRE) of human MECP2.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution.
StorageThis antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label orCoAto find the proper storage conditions.
Regulatory StatusResearch Use Only
Scientific Background
Methyl CpG binding protein (MECP2), also known as autism susceptibility to X-linked 2 (AUTSX3), is a nuclear protein crucial for normal neuronal function that binds to methylated DNA, forming complexes with histone deacteylases and turning off gene expression. MECP2 expression is an X-linked trait. Loss of MECP2 expression causes Rett Syndrome (also known as RTS, RTT, or RS) a neurological disorder which causes decelerated growth of hands, feet, and the head.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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