Purified anti-MEK1 Phospho (Ser298) Antibody, MEK1 Phospho (Ser298), A16117B,BioLegend,610601
Host
Mouse
Reactivity
Human, Mouse
Application
WB -Quality testedICFC -Verified
Platform ID
BAB236287201
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-MEK1 Phospho (Ser298) Antibody, MEK1 Phospho (Ser298), A16117B
Cat. No.610601
HostMouse
RRIDAB_2810657 (BioLegend Cat. No. 610601)AB_2810658 (BioLegend Cat. No. 610602)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse
ApplicationWB -Quality testedICFC -Verified
ClonalityMonoclonal
Clone NumberA16117B
Concentration0.5 mg/mL
TargetMEK1 Phospho Ser298
ImmunogenHuman MEK1 peptide phosphorylated at Ser298. Complete Freund’s adjuvant.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
MEK1 and MEK2 (Map/Erk Kinase) are serine/threonine kinases in the MAPK/ERK signaling axis that play a critical role in cellular proliferation, differentiation, and migration. Phosphorylation at MEK1 (Ser298) by PAK1 enhances the ability of upstream Raf kinases to phosphorylate regulatory serines (Ser218 and Ser222) in the activation loop, thereby stimulating kinase activity.
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