Purified anti-Maf Antibody, Maf, W18010A,BioLegend,603451
This clone has been tested and does not work for IHC-P.For ICC application, paraformaldehyde plus Triton-X and paraformaldehyde plus methanol fix/perm methods are recommended. The use of methanol only as fix/perm is not suitable for this antibody.For ICFC application, Cyto-Fast™ Fix/Perm Buffer Set (Cat. No. 426803) is recommended.
Host
Rat
Reactivity
Human
Application
WB - Quality testedICC, ICFC - Verified
Platform ID
BAB893284335
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
Transcription factor Maf (Maf) is a transcription factor encoded by the MAF gene. In a complex as a homo- or hetero-dimer, Maf acts as a transcriptional activator and repressor with diverse functions. For example, Maf plays numerous roles in the immune system by regulating IL-4 expression and modulating T-cell apoptosis, and is also a critical regulator of glucagon production in pancreatic alpha cells. Additionally, Maf plays a role in the development of multiple tissues, including the eye, bone, and blood vessels. Mutations in Maf are known to cause congenital and juvenile cataracts.
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