Purified anti-Myogenin Antibody, Myogenin, F5D,BioLegend,608851

This product was tested for use in immunocytochemistry and flow cytometry in HeLa and RD cells but did not meet passing criteria.This product was tested for use in IHC-P in human and mouse skeletal muscle tissue but did not meet passing criteria.

Host

Mouse

Reactivity

Human, Mouse

Application

WB - Quality tested

Platform ID

BAB722355156

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePurified anti-Myogenin Antibody, Myogenin, F5D
Cat. No.608851
HostMouse
RRIDAB_2927974 (BioLegend Cat. No. 608851)AB_2927974 (BioLegend Cat. No. 608852)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse
ApplicationWB - Quality tested
ClonalityMonoclonal
Clone NumberF5D
Concentration0.5 mg/mL
TargetMyogenin
ImmunogenSynthetic peptide containing a fragment of the N-terminus of rat myogenin
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Myogenin is a basic helix-loop-helix transcription factor from the myogenic regulator factor (MRF) family of transcription factors, which also includes MyoD, Myf5 and MRF4. Like other members of the MRF family myogenin is required for skeletal muscle development, and regulates the growth, repair and atrophy of skeletal muscle and myosatellite cells. In mice, loss of myogenin expression results in perinatal lethality resulting from major deficits in skeletal muscle formation. In humans, myogenin has diagnostic value as a marker for rhabdomyosarcoma and other related cancers.

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