Purified anti-NOS1, NOS1, W19138A,BioLegend,602851

This product was tested and failed for IHC-F in mouse brain.

Host

Rat

Reactivity

Human, Mouse

Application

WB - Quality testedIHC-P - Verified

Platform ID

BAB395833111

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-NOS1, NOS1, W19138A
Cat. No.602851
HostRat
RRIDAB_2910479 (BioLegend Cat. No. 602851)AB_2910479 (BioLegend Cat. No. 602852)
IsotypeRat IgG2a, κ
ReactivityHuman, Mouse
ApplicationWB - Quality testedIHC-P - Verified
ClonalityMonoclonal
Clone NumberW19138A
Concentration0.5 mg/mL
TargetNOS1
ImmunogenRecombinant fragment of human NOS1 protein
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Nitric oxide synthase 1 (NOS1) catalyzes the formation of nitric oxide (NO) from L-arginine. NO signals in neurons intracellularly to regulate metabolic activity and dendrite growth. NO also functions in neurons as a neurotransmitter-like signaling molecule, and in muscle cells, where it is a potent relaxer. High concentrations of NO are cytotoxic, so it is utilized by macrophages as a bactericide/tumoricide, and it has also been implicated in the progression of neurodegenerative disorders like Alzheimer’s.

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