Purified anti-Nestin Antibody, Nestin, Poly22A17,BioLegend,626351
For Immunocytochemistry, either 4% paraformaldehyde/Triton X-100, 4% paraformaldehyde/methanol, or methanol only is recommended for fixation/permeabilization.
Host
Rabbit
Reactivity
Human
Application
ICC - Quality testedWB - Verified
Platform ID
BAB061437376
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePurified anti-Nestin Antibody, Nestin, Poly22A17
Cat. No.626351
HostRabbit
RRIDAB_3097319 (BioLegend Cat. No. 626351)AB_3097319 (BioLegend Cat. No. 626352)
IsotypeRabbit Polyclonal IgG
ReactivityHuman
ApplicationICC - Quality testedWB - Verified
ClonalityPolyclonal
Clone NumberPoly22A17
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetNestin
ImmunogenRecombinant fragment of human nestin
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
Nestin is a class VI intermediate filament protein originally found in neuronal stem cells, and is required for survival and renewal of neural progenitor cells. In mixtures, Nestin forms heterodimers with vimentin or internexin, participating in the remodeling of the cell. Nestin was found to be expressed on vascular endothelial progenitor cells and various neoplasms. It is proposed to be a novel angiogenesis marker and cancer therapeutic target.
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