Purified anti-Neu1 Antibody, Neu1, A18167C,BioLegend,623852

Neu1, a member of the sialidase enzyme family, plays a crucial role in cellular processes by removing sialic acid (N-acetylneuraminic acid) residues from glycoproteins and glycolipids on the cell surface. This process, known as desialylation, impacts various cellular functions, including cell-cell interactions, signal transduction, and immune responses. Additionally, desialylation recycles sialic acid, contributing to the maintenance of cellular sialic acid levels critical for normal physiological processes. Alterations in Neu1 activity leads to sialidosis, a lysosomal storage disease resulting in an accumulation of sugar-protein complexes.