Purified anti-Parkin Antibody anti-Parkin - Prk 8,BioLegend,808503

This antibody is reactive to the R2 domain of human and murine parkin.

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB -Quality testedICC, IHC-P -Reported in the literature, not verified in house

Platform ID

BAB767533460

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePurified anti-Parkin Antibody anti-Parkin - Prk 8
Cat. No.808503
HostMouse
RRIDAB_2810708 (BioLegend Cat. No. 808504)AB_2564744 (BioLegend Cat. No. 808501)AB_2564745 (BioLegend Cat. No. 808502)AB_2564743 (BioLegend Cat. No. 808503)
IsotypeMouse IgG2b, κ
ReactivityHuman, Mouse, Rat
ApplicationWB -Quality testedICC, IHC-P -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberPrk 8
Concentration0.5 mg/ml
TargetParkin
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution (no preservatives or carrier proteins).
StorageThis antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label orCoAto find the proper storage conditions.
Regulatory StatusResearch Use Only

Scientific Background

Parkin (also known as PARK2, AR-JP, PRKN) is a protein encoded by the PARK2 gene in humans. It is a component of the E3 ubiquitin ligase complex that mediates the targeting of proteins for degradation. Mutations in the PARK2 gene cause a familial form of Parkinson’s disease called autosomal recessive juvenile Parkinson’s disease (AR-JP).

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