Purified anti-Podoplanin Lymphatic Endothelial Marker Antibody anti-Podoplanin - D2-40,BioLegend,916605

Additional reported applications (for the relevant formats) include: ELISA Detection5and immunocytochemistry4.

Host

Mouse

Reactivity

Human

Application

IHC-P - Quality testedWB, ICFC, ICC - VerifiedELISA Detection - Reported in the literature, not verified in house

Platform ID

BAB779838815

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePurified anti-Podoplanin Lymphatic Endothelial Marker Antibody anti-Podoplanin - D2-40
Cat. No.916605
HostMouse
RRIDAB_2565819 (BioLegend Cat. No. 916605)AB_2565820 (BioLegend Cat. No. 916606)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationIHC-P - Quality testedWB, ICFC, ICC - VerifiedELISA Detection - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberD2-40
Concentration1.0 mg/mL
TargetPodoplanin
ImmunogenM2A protein derived from human germ cell tumors.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Podoplanin is expressed by a variety of normal cells, which include breast and prostate myopepithelial cells, follicular dendritic cells, basal keratinocytes of the skin and cervix (focal), type I pneumocytes, ependymal cells, and fetal cerebral germinal matrix cells. Podoplanin is a marker of lymphatic differentiation because it is expressed by normal human lymphatic endothelium, but not by vascular endothelium. It is diagnostically a useful marker for the evaluation of a variety of neoplasms, including Kaposi sarcoma mesothelioma, testicular germ cell tumors, and cutanneous sebaceous neoplasms.

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