Purified anti-SOD1 Antibody anti-SOD1 - O98B10,BioLegend,850701
Reactivity to Drosophila was only verified with the purified format.
Host
Mouse
Reactivity
Human, Mouse, Rat, Drosophila
Application
WB -Quality tested
Platform ID
BAB074442395
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePurified anti-SOD1 Antibody anti-SOD1 - O98B10
Cat. No.850701
HostMouse
RRIDAB_2716015 (BioLegend Cat. No. 850701)AB_2716016 (BioLegend Cat. No. 850702)
IsotypeMouse IgG2b, κ
ReactivityHuman, Mouse, Rat, Drosophila
ApplicationWB -Quality tested
ClonalityMonoclonal
Clone NumberO98B10
Concentration0.5 mg/ml
TargetSOD1
ImmunogenFull-length human SOD1 expressed in 293T cells transfected with human SOD1 expression vector.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
Superoxide dismutase 1 (SOD1) is one of three isozymes responsible for destroying free superoxide radicals in the body. SOD1 is a homodimeric cytoplasmic Cu/Zn binding protein that converts harmful superoxide radicals to oxygen and hydrogen peroxide. The other isozymes are SOD2 and SOD3, which are localized to the mitochondria and extracellular space, respectively. SOD1 mutations are associated with familial amyotrophic lateral sclerosis.
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