Purified anti-α Smooth Muscle Actin Antibody, α Smooth Muscle Actin, 1A4,BioLegend,614851
Host
Mouse
Reactivity
Human, Mouse
Application
IHC-P - Quality testedICC, WB, ICFC - Verified
Platform ID
BAB043768390
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-α Smooth Muscle Actin Antibody, α Smooth Muscle Actin, 1A4
Cat. No.614851
HostMouse
RRIDAB_2941620 (BioLegend Cat. No. 614851)AB_2941620 (BioLegend Cat. No. 614852)
IsotypeMouse IgG2a, κ
ReactivityHuman, Mouse
ApplicationIHC-P - Quality testedICC, WB, ICFC - Verified
ClonalityMonoclonal
Clone Number1A4
Concentration0.5 mg/mL
Targetalpha Smooth Muscle Actin
ImmunogenN-terminal synthetic peptide of alpha-smooth muscle actin coupled to keyhole limpet haemocyanin (KLH).
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
Cytoplasmic actins, which belong to the microfilament system of cytoskeleton proteins, are some of the most conserved eukaryotic proteins expressed in mammals. α-smooth muscle actin is widely expressed in contractile cells, most notably the mural cells that line arteries and arterioles. Overexpression of α-smooth muscle actin is a hallmark of fibrosis, a thickening or scarring of damaged tissue.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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