Purified anti-Tubulin beta 3 TUBB3 Antibody anti-Tubulin beta 3 (TUBB3) - TUJ1,BioLegend,801202

Additional reported applications (for the relevant formats) include: flow cytometry4, immunofluorescence microscopy1-5,7, immunohistochemistry5,7, Western blotting8, and spatial biology (IBEX)9,10.This antibody is well characterized and highly reactive to neuron specific Class III ß-tubulin (ßIII). TUJ1 does not identify ß-tubulin found in glial cells. TUJ1 recognizes an epitope located within the last 15 C-terminal residues8.

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

IHC-P -Quality testedWB, ICC -VerifiedFC -Reported in the literature, not verified in houseSB -Community verified

Platform ID

BAB596881619

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePurified anti-Tubulin beta 3 TUBB3 Antibody anti-Tubulin beta 3 (TUBB3) - TUJ1
Cat. No.801202
HostMouse
RRIDAB_2313773 (BioLegend Cat. No. 801213)AB_2313773 (BioLegend Cat. No. 801201)AB_2313773 (BioLegend Cat. No. 801202)
IsotypeMouse IgG2a, κ
ReactivityHuman, Mouse, Rat
ApplicationIHC-P -Quality testedWB, ICC -VerifiedFC -Reported in the literature, not verified in houseSB -Community verified
ClonalityMonoclonal
Clone NumberTUJ1
Concentration1.0 mg/ml
TargetTubulin beta-3
ImmunogenThis antibody was raised against microtubules derived from rat brain.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.Previous lots (B465167 and prior) of this product may have been formulated in Phosphate-buffered solution + 0.03% Thimerosal. For further information please contact BioLegendTechnical SupportorCustomer Service.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Regulatory StatusResearch Use Only

Scientific Background

Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.

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