Purified anti-UBE2V1 Antibody, UBE2V1, A18196A,BioLegend,870702
Host
Mouse
Reactivity
Human, Mouse, Rat, Drosophila
Application
WB -Quality tested
Platform ID
BAB739135833

BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Specifications
Scientific Background
Ubiquitination is a common post-translational modification of proteins and plays an important role in protein homeostasis.UBE2V1encodes one of the ubiquitin-conjugating E2 enzyme variant proteins (UBE2V), which lacks the conserved cysteine residue required for the catalytic activity of E2s. Elevated expression of UBE2V1 has been associated with tumor development; however, it is not clear whether it functions as an oncogene or tumor suppressor gene. In addition, UBE2V1 is a key component in TRAF6 to control NF-κB activation.
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