Purified anti-UBE2V1 Antibody, UBE2V1, A18196A,BioLegend,870702

Host

Mouse

Reactivity

Human, Mouse, Rat, Drosophila

Application

WB -Quality tested

Platform ID

BAB739135833

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-UBE2V1 Antibody, UBE2V1, A18196A
Cat. No.870702
HostMouse
RRIDAB_2832874 (BioLegend Cat. No. 870701)AB_2832875 (BioLegend Cat. No. 870702)
IsotypeMouse IgG2a, κ
ReactivityHuman, Mouse, Rat, Drosophila
ApplicationWB -Quality tested
ClonalityMonoclonal
Clone NumberA18196A
Concentration0.5 mg/mL
TargetUBE2V1
ImmunogenRecombinant human UBE2V1 protein
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Ubiquitination is a common post-translational modification of proteins and plays an important role in protein homeostasis.UBE2V1encodes one of the ubiquitin-conjugating E2 enzyme variant proteins (UBE2V), which lacks the conserved cysteine residue required for the catalytic activity of E2s. Elevated expression of UBE2V1 has been associated with tumor development; however, it is not clear whether it functions as an oncogene or tumor suppressor gene. In addition, UBE2V1 is a key component in TRAF6 to control NF-κB activation.

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