Purified anti-c-Fos Antibody, c-Fos, W23257D,BioLegend,657051

Host

Rat

Reactivity

Human, Mouse

Application

WB - Quality testedICC, ICFC - Verified

Platform ID

BAB150206011

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-c-Fos Antibody, c-Fos, W23257D
Cat. No.657051
HostRat
RRIDAB_3717128 (BioLegend Cat. No. 657051)AB_3717128 (BioLegend Cat. No. 657052)
IsotypeRat IgG2b, λ
ReactivityHuman, Mouse
ApplicationWB - Quality testedICC, ICFC - Verified
ClonalityMonoclonal
Clone NumberW23257D
Concentration0.5 mg/mL
Targetc-Fos
ImmunogenRecombinant fragment of human c-Fos
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

The c-Fos protein, or FBJ murine viral (v-Fos) oncogene homolog, is a member of the Fos family of transcription factors. c-Fos forms heterodimers with proteins of the Jun family of transcription factors to form the AP-1 (Activator Protein-1) complex, which regulates critical cellular processes, including cell proliferation, differentiation, and survival. C-Fos has been demonstrated to play a critical role in angiogenesis, bone development, and in the progression of cancer. C-Fos is also often used as an indirect marker of neuronal activity.

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