Purified anti-human CCL22 Antibody, CCL22, A15083D,BioLegend,694402

Clones A15083A and A15083D do not block each otherClone A15083A does not block the reference clone T51-719 (BD Bioscience)Clones A15083A and A15083D showed good staining in both Cyto-Fast™ Fix/Perm Buffer Set and True-Phos™ Perm Buffer.

Host

Mouse

Reactivity

Human

Application

Direct ELISA - Quality tested

Platform ID

BAB296769420

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Product Specifications
Scientific Background

Specifications

NamePurified anti-human CCL22 Antibody, CCL22, A15083D
Cat. No.694402
HostMouse
RRIDAB_2941631 (BioLegend Cat. No. 694402)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationDirect ELISA - Quality tested
ClonalityMonoclonal
Clone NumberA15083D
Concentration0.5 mg/mL
TargetCCL22
ImmunogenHuman CCL22
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CCL22 is thymus-specific chemokine engaged in the recruitment of T cells. CCL22 is associated with different diseases such as allergen-induced lung inflammation, atopic dermatitis, and lymphoma. Also, high levels of CCL22 have been detected in the CNS in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). In addition, CCR4+ T cells have been linked to endotoxic shock, rheumatoid arthritis, T cell lymphoma, and autoimmune diabetes. CCL22 is a prostaglandin-dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue.

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