Purified anti-human CD123 Recombinant Antibody, CD123, QA18A25,BioLegend,365402
Clone QA18A25 can completely block the binding of clone 6H6 on target cells.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB956676421
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human CD123 Recombinant Antibody, CD123, QA18A25
Cat. No.365402
HostMouse
RRIDAB_2894592 (BioLegend Cat. No. 365402)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA18A25
Concentration0.5 mg/mL
TargetCD123
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
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