Purified anti-human CD1d Antibody anti-CD1d - 51.1,BioLegend,350302

Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1, Western blotting1,2, and induction of IL-12 production by crosslinking of CD1d3.

Host

Mouse

Reactivity

Human

Application

FC -Quality testedIHC-F, IP, Stim, WB -Reported in the literature, not verified in house

Platform ID

BAB000977675

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePurified anti-human CD1d Antibody anti-CD1d - 51.1
Cat. No.350302
HostMouse
RRIDAB_10641848 (BioLegend Cat. No. 350302)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC -Quality testedIHC-F, IP, Stim, WB -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone Number51.1
Concentration0.5 mg/ml
TargetCD1d
ImmunogenHuman CD1d-Fc fusion
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CD1d is a MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily. On the cell surface, CD1d forms a heterodimer with β2-microglobulin. CD1d is expressed by antigen-presenting cells such as B cells, monocytes/macrophages, dendritic cells, and some non-lymphoid cells. Cortical thymocytes express CD1d but the expression is lost in mature T cells. CD1d presents lipid antigens toiNKT cells analogous to MHC molecule presentation of peptides to T cells.

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