Purified anti-human CD3 Antibody anti-CD3 - SK7,BioLegend,344802

Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.

Host

Mouse

Reactivity

Human

Application

FC -Quality testedICC, IHC-F, WB -Reported in the literature, not verified in house

Platform ID

BAB467121405

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-human CD3 Antibody anti-CD3 - SK7
Cat. No.344802
HostMouse
RRIDAB_2043994 (BioLegend Cat. No. 344801)AB_2043995 (BioLegend Cat. No. 344802)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality testedICC, IHC-F, WB -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberSK7
Concentration0.5 mg/ml
TargetCD3
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T cells, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

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