Purified anti-human CD339 (Jagged 1) Antibody, CD339, W16199B,BioLegend,399102
Host
Rat
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB266872513
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human CD339 (Jagged 1) Antibody, CD339, W16199B
Cat. No.399102
HostRat
RRIDAB_2832781 (BioLegend Cat. No. 399102)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberW16199B
Concentration0.5 mg/mL
TargetCD339
ImmunogenHuman Jagged-transfected RBL1 cells
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD339, also known as Jagged 1, is a 135 kDa type 1 transmembrane protein with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. Jagged 1 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Some studies suggest Jagged 1 is also involved in Th2 polarization and Treg induction.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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