Purified anti-human CD41 Maxpar Ready Antibody anti-CD41 - HIP8,BioLegend,303721
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and blocking of platelet aggregation2. The HIP8 antibody has been reported to block the activation of platelets by various stimuli, including collagen, and ADP.
Host
Mouse
Reactivity
Human
Application
FC - Quality testedCyTOF® - Verified
Platform ID
BAB295881111
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human CD41 Maxpar Ready Antibody anti-CD41 - HIP8
Cat. No.303721
HostMouse
RRIDAB_2562820 (BioLegend Cat. No. 303721)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality testedCyTOF® - Verified
ClonalityMonoclonal
Clone NumberHIP8
Concentration1.0 mg/ml
TargetCD41
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, and thrombin.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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