Purified anti-human CD43 Antibody, CD43, MT1,BioLegend,314311

Host

Mouse

Reactivity

Human

Application

FC - Quality testedIHC-P - Verified

Platform ID

BAB007763152

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-human CD43 Antibody, CD43, MT1
Cat. No.314311
HostMouse
RRIDAB_3698971 (BioLegend Cat. No. 314311)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality testedIHC-P - Verified
ClonalityMonoclonal
Clone NumberMT1
Concentration0.5 mg/mL
TargetCD43
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CD43, also known as Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein, and W3/13, is a large single chain, type I transmembrane glycoprotein with abundant O-glycosylation and sialylation sites. It has been reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesion and anti-adhesion as well as costimulation of T cell activation and survival, and induction of apoptosis of T cells and hematopoietic progenitors.

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