Purified anti-human CD56 NCAM Antibody anti-CD56 - HCD56,BioLegend,318302

Clone HCD56 is not recommended for immunohistochemistry formalin-fixed paraffin-embedded tissue.

Host

Mouse

Reactivity

Human

Application

FC - Quality testedCyTOF® - Verified

Platform ID

BAB464011634

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Product Specifications
Scientific Background

Specifications

NamePurified anti-human CD56 NCAM Antibody anti-CD56 - HCD56
Cat. No.318302
HostMouse
RRIDAB_604092 (BioLegend Cat. No. 318302)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality testedCyTOF® - Verified
ClonalityMonoclonal
Clone NumberHCD56
Concentration0.5 mg/ml
TargetCD56
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.

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