Purified anti-human CD73 Ecto-5-nucleotidase Antibody anti-CD73 - AD2,BioLegend,344002
Additional reported applications (for the relevant formats) include:immunofluorescence3.Clone AD2 has been noted to induce clustering and internalization of CD73in vivoand inhibit metastasis in a murine breast cancer xenograft model4.
Host
Mouse
Reactivity
Human
Application
FC -Quality testedIHC-F -VerifiedBlock -Reported in the literature, not verified in house
Platform ID
BAB703963988
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human CD73 Ecto-5-nucleotidase Antibody anti-CD73 - AD2
Cat. No.344002
HostMouse
RRIDAB_2154067 (BioLegend Cat. No. 344002)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality testedIHC-F -VerifiedBlock -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberAD2
Concentration0.5 mg/ml
TargetCD73
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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