Purified anti-human CD80 Recombinant Antibody, CD80, QA18A16,BioLegend,370610
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB831513999
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NamePurified anti-human CD80 Recombinant Antibody, CD80, QA18A16
Cat. No.370610
HostMouse
RRIDAB_2892452 (BioLegend Cat. No. 370610)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA18A16
Concentration0.5 mg/mL
TargetCD80
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.