Purified anti-human GPR83 Antibody anti-GPR83 - K07JP05,BioLegend,363302
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB491620904
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human GPR83 Antibody anti-GPR83 - K07JP05
Cat. No.363302
HostMouse
RRIDAB_2564189 (BioLegend Cat. No. 363302)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberK07JP05
Concentration0.5 mg/ml
TargetGPR83
ImmunogenDNA vaccine with full coding sequence of human GPCR cloned in expression vector.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
GPR83, also known as GIR, is a seven-pass membrane protein that belongs to the G-protein coupled receptor 1 family. GPR83 is an orphan GPR homologous to tachykinin and neuropeptide Y (NPY) receptors. GPR83 is expressed in the brain and in both murine and human Treg cells. GPR83 is reported to regulate core body temperature and there are four isoforms of GPR83. Studies have suggested that isoform-4, but not isoform-1, is associated with the suppressive functions of Treg cells. The precise role of GPR83 in Treg function is unclear.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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