Purified anti-human HVCN1 Antibody, HVCN1, W23068A,BioLegend,377106

Host

Rat

Reactivity

Human

Application

ICFC - Quality tested

Platform ID

BAB024843685

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-human HVCN1 Antibody, HVCN1, W23068A
Cat. No.377106
HostRat
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberW23068A
Concentration0.5 mg/mL
TargetHVCN1
ImmunogenRecombinant human HVCN1
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

HVCN1 (hydrogen voltage-gated channel 1), is a voltage gated proton-selective channel. HVCN1 is expressed in immune cells, spermatozoa, and upper respiratory tract epithelial cells. HVCN1 mediates the proton conductance required to maintain inhibition of membrane depolarization and acidification of cytoplasm. HVCN1 is required by phagocytes for oxidative burst that underlies microbial killing and in B cells to facilitates antibody production. HVCN1 can also regulate functions in other cells including spermatozoa.

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