Purified anti-human ICAM-2 Antibody, ICAM-2, Poly5440,BioLegend,544001
This product is not suitable for IHC-P.This product does not cross-react with human ICAM-1 in Western Blot.
Host
Goat
Reactivity
Human
Application
WB - Quality tested
Platform ID
BAB311962124
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human ICAM-2 Antibody, ICAM-2, Poly5440
Cat. No.544001
HostGoat
RRIDAB_2941599 (BioLegend Cat. No. 544001)
IsotypeGoat Polyclonal IgG
ReactivityHuman
ApplicationWB - Quality tested
ClonalityPolyclonal
Clone NumberPoly5440
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetICAM-2
ImmunogenRecombinant fragment of human ICAM-2
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
Intracellular adhesion molecule 2 (ICAM2) is a type I transmembrane glycoprotein that mediates cell-cell adhesions. Specifically, ICAM2 binds to LFA-1, a member of the integrin family primarily expressed by lymphocytes. ICAM2 expression regulates the migration of leukocytes and neutrophils via cell-cell interactions and plays an important role in their development and immune response. Additionally, ICAM2 controls the adhesion of developing sperm in the testis and is important for proper spermatogenesis.
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