Purified anti-human IFN-gamma Maxpar Ready Antibody anti-IFN-gamma - B27,BioLegend,506521

Flow Cytometry2:The fluorochrome-labeled B27 antibody is useful for intracellular immunofluorescent staining and flow cytometric analysis to identify IFN-? -producing cells within mixed cell populations. For intracellular cytokine staining protocol, please visit www.biolegend.com and click on the support section.Neutralization1,3,6,7:The Ultra-LEAF™Purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IFN-? bioactivity (Cat. No. 506531).

Host

Mouse

Reactivity

Human

Application

ICFC - Quality testedCyTOF® - Verified

Platform ID

BAB769643711

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-human IFN-gamma Maxpar Ready Antibody anti-IFN-gamma - B27
Cat. No.506521
HostMouse
RRIDAB_2562849 (BioLegend Cat. No. 506521)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICFC - Quality testedCyTOF® - Verified
ClonalityMonoclonal
Clone NumberB27
Concentration1.0 mg/ml
TargetIFN-gamma
ImmunogenE. coli-expressed recombinant human IFN-γ
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells. The B27 antibody reacts with the human interferon-γ. The B27 antibody can neutralize the bioactivity of natural or recombinant IFN-γ.

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