Purified anti-human IL-10 Antibody anti-IL-10 - JES3-12G8,BioLegend,501505
ELISA Detection1-4or ELISPOT Detection5:The biotinylated JES3-12G8 antibody is useful as a detection antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the Ultra-LEAF™ purified JES3-9D7 antibody (Cat. Nos. 501427 & 501428) or purified JES3-19F1 antibody (Cat. No. 506802/506810) as capture antibody and recombinant human IL-10 (Cat. No. 571009) as the standard.Additional reported applications (for the relevant formats) include:immunohistochemical staining6,7of paraformaldehyde-fixed, saponin-treated frozen tissue sections, neutralization, and immunocytochemistry.Note:For testing human IL-10 in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. Nos. 430601 & 430606) are specially developed and recommended.
Host
Rat
Reactivity
Human
Application
ELISA - Quality testedICFC - VerifiedIHC - Reported in the literature, not verified in house
Platform ID
BAB365159106
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production. The JES3-12G8 antibody reacts with human and viral interleukin-10 (IL-10). The JES3-12G8 antibody can neutralize the bioactivity of natural or recombinant IL-10.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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