Purified anti-human IL-4 Antibody anti-IL-4 - 8D4-8,BioLegend,500701
Additional reported applications (for the relevant formats) include: ELISPOT Capture, neutralization, intracellular staining for flow cytometry, immunohistochemical staining, and immunoprecipitation.
Host
Mouse
Reactivity
Human
Application
ELISA Capture -Quality testedELISPOT Capture, Neut, ICFC, IHC, IP -Reported in the literature, not verified in house
Platform ID
BAB135535585
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
IL-4 is a pleiotropic cytokine that is produced by activated T cells mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naïve CD4+T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. The 8D4-8 antibody can neutralize the bioactivity of natural or recombinant IL-4.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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