Purified anti-human IL-6 Antibody anti-IL-6 - MQ2-39C3,BioLegend,501204
ELISA or ELISPOT Detection1-4:The biotinylated MQ2-39C3 antibody is useful as a detection antibody for a sandwich ELISA or ELISPOT assay, when used in conjunction with purified MQ2-13A5 antibody (Cat. No. 501101/501102) as the capture antibody.Additional reported applications (for the relevant formats) include:neutralization1, Western blotting. The LEAF™ purified MQ2-13A5 antibody (EndotoxinNote:For testing human IL-6 in serum or plasma, BioLegend's ELISA Max™ Sets (Cat. No. 430501 to 430506) are specially developed and recommended.
Host
Rat
Reactivity
Human
Application
ELISA, WB
Platform ID
BAB882600730
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-human IL-6 Antibody anti-IL-6 - MQ2-39C3
Cat. No.501204
HostRat
RRIDAB_2296206 (BioLegend Cat. No. 501204)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationELISA, WB
ClonalityMonoclonal
Clone NumberMQ2-39C3
Concentration0.5 mg/ml
TargetIL-6
ImmunogenCOS-7- expressed, recombinant human IL-6
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survival of certain B cells and T cells. IL-6 plays a role in host defense, acute phase reactions, immune response, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes. The MQ2-39C3 antibody can neutralize the bioactivity of natural or recombinant IL-6.
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