Purified anti-human NGF Antibody anti-NGF - JKhNGF-1,BioLegend,509602

ELISA Capture:The purified JKhNGF-1 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated JKhNGF-2 antibody (Cat. No. 509802) as the detecting antibody for detecting human NGF.

Host

Mouse

Reactivity

Human

Application

ELISA Capture - Quality tested

Platform ID

BAB589673816

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePurified anti-human NGF Antibody anti-NGF - JKhNGF-1
Cat. No.509602
HostMouse
RRIDAB_315541 (BioLegend Cat. No. 509601)AB_315542 (BioLegend Cat. No. 509602)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationELISA Capture - Quality tested
ClonalityMonoclonal
Clone NumberJKhNGF-1
Concentration0.5 mg/ml
TargetNGF
Immunogenrecombinant human NGF (a.a. 58-68)
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Nerve growth factor (NGF) is a small secreted protein that is important for the growth, maintenance, and survival of certain target neurons (nerve cells). NGF consists of three types of subunits, α, β and γ, which specifically interact to form a 7S, 130,000 molecular weight complex. This complex contains two identical 118-amino acid β-chains, which are solely responsible for nerve growth stimulating activity of NGF. NGF is essential for the development and phenotypic maintenance of neurons in the peripheral nervous system (PNS) and for the functional integrity of cholinergic neurons in the central nervous system (CNS).

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