Purified anti-human PSMA FOLH1 Antibody anti-PSMA - LNI-17,BioLegend,342502

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB182912833

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePurified anti-human PSMA FOLH1 Antibody anti-PSMA - LNI-17
Cat. No.342502
HostMouse
RRIDAB_1626138 (BioLegend Cat. No. 342502)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberLNI-17
Concentration0.5 mg/ml
TargetPSMA
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

PSMA (prostate-specific membrane antigen) is a type II transmembrane zinc metallopeptidase, belonging to the M28 peptidase family. It possesses hydrolyzing enzyme activities and is also known as FOLH1 (folate hydrolase 1), GCP2 (glutamate carboxypeptidase II), and NAALADase I (N-acetylated-alpha-linked acidic dipeptidase I). PSMA is expressed by normal and malignant prostate epithelial cells, by urothelial adenocarcinoma, and vasculatures of other malignancies. It is also found in the nervous system.

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