Purified anti-mouse CD100 SEMA4D Antibody anti-CD100 - BMA-12,BioLegend,147601

Additional reported applications for the relevant formats include: immunoprecipitation from cell lysates2, capture antibody function in a sandwich ELISA assay2, and immunohistochemical staining of frozen brain sections4.

Host

Rat

Reactivity

Mouse

Application

FC -Quality testedIHC-F -VerifiedIP, ELISA -Reported in the literature, not verified in house

Platform ID

BAB023266971

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-mouse CD100 SEMA4D Antibody anti-CD100 - BMA-12
Cat. No.147601
HostRat
RRIDAB_2563413 (BioLegend Cat. No. 147601)AB_2563414 (BioLegend Cat. No. 147602)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality testedIHC-F -VerifiedIP, ELISA -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberBMA-12
Concentration0.5 mg/ml
TargetCD100
ImmunogenMouse CD100-Fc fusion protein
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CD100, also known as Semaphorin-4D (SEMA4D), is a 150 kD, type I transmembrane protein, with one sema domain and one C2-type Ig domain. It is found as a homodimer on the cell surface. CD100 is expressed in the brain, kidney, heart, the majority of hematopoietic cells, and some malignant cells. CD100 is a potent inducer of angiogenesis and inhibitor of bone formation, and plays a role in lymphocyte activation, antibody production, dendritic cell maturation, and axon guidance. Its ligands are CD72 and Plexin-B1. CD100 is cleaved from the membrane of activated T and B cells, producing a soluble form.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.