Purified anti-mouse CD144 VE-cadherin Antibody anti-CD144 - BV13,BioLegend,138001
Clone BV13 recognizes an epitope between aa 45 and 56, and has a binding affinity of 5-15 nM5. Additional reported applications (for relevant formats) include: Western blotting1, blocking of cell interactionsin vivo1, and immunofluorescence microscopystaining4.
Host
Rat
Reactivity
Mouse
Application
FC -Quality testedWB, ICC, Block -Reported in the literature, not verified in house
Platform ID
BAB024566347
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePurified anti-mouse CD144 VE-cadherin Antibody anti-CD144 - BV13
Cat. No.138001
HostRat
RRIDAB_10570497 (BioLegend Cat. No. 138001)AB_10569559 (BioLegend Cat. No. 138002)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationFC -Quality testedWB, ICC, Block -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberBV13
Concentration0.5 mg/ml
TargetCD144
ImmunogenVE-cadherin-Ig fusion protein
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD144, also known as vascular endothelial-cadherin (VE-cadherin), is a 120 kD member of the type II Cadherin family. It is an endothelial specific hemophilic adhesion molecule involved in endothelial cell survival, migration, contact-dependent growth inhibition, and homophilic adhesion. VE-cadherin is essential for maintaining the integrity of the endothelial barrierin vivo.
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