Purified anti-mouse CD18 Antibody anti-CD18 - C71/16,BioLegend,830501

This antibody is effective in flow cytometry (FC).*FC Positive Control: Mouse bloodRat IgG2a Isotype antibody available: Catalog number: 910601

Host

Rat

Reactivity

Mouse

Application

FC

Platform ID

BAB651577881

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Product Specifications
Scientific Background

Specifications

NamePurified anti-mouse CD18 Antibody anti-CD18 - C71/16
Cat. No.830501
HostRat
RRIDAB_2564939 (BioLegend Cat. No. 830501)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC
ClonalityMonoclonal
Clone NumberC71/16
Concentration1 mg/ml
TargetCD18
ImmunogenThis monoclonal antibody was raised against cell membrane glycoproteins derived from T-cell lymphoma BW5147 cells.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution.
StorageThis antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label orCoAto find the proper storage conditions.
Regulatory StatusResearch Use Only

Scientific Background

CD18 is a 95 kD protein, also known as integrin β2subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

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