Purified anti-mouse CD1d CD1.1, Ly-38 Antibody anti-CD1d - 1B1,BioLegend,123502

Additional reported applications (for the relevant formats) include: immunoprecipitation, immunohistochemistical staining, and blocking function3.This product is for research use only and is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact the Regents of the University of California.

Host

Rat

Reactivity

Mouse

Application

FC - Quality testedIHC, IP - Reported in the literature, not verified in house

Platform ID

BAB419455560

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePurified anti-mouse CD1d CD1.1, Ly-38 Antibody anti-CD1d - 1B1
Cat. No.123502
HostRat
RRIDAB_1236531 (BioLegend Cat. No. 123502)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality testedIHC, IP - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone Number1B1
Concentration0.5 mg/ml
TargetCD1d
ImmunogenMouse CD1.1 cDNA-transfected RMA-S mouse T lymphoma
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD1d, also known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein that is structurally similar to MHC class I and is non-covalently associated with β2-microglobulin. In humans, the CD1 family consists of group I (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e) proteins, but CD1d is the only CD1 molecule found in mice. Mouse CD1d has broad tissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes. CD1d plays a role in presenting non-peptide glycolipid antigens to CD1d-restricted T cells, and PKCδ has been identified as a critical regulator of CD1d-mediated antigen presentation.

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