Purified anti-mouse CD226 DNAM-1 Antibody anti-CD226 - 10E5,BioLegend,128822
Host
Rat
Reactivity
Mouse
Application
FC -Quality testedIHC-F -Verified
Platform ID
BAB975389963
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePurified anti-mouse CD226 DNAM-1 Antibody anti-CD226 - 10E5
Cat. No.128822
HostRat
RRIDAB_2728146 (BioLegend Cat. No. 128822)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC -Quality testedIHC-F -Verified
ClonalityMonoclonal
Clone Number1000000
Concentration0.5 mg/ml
TargetCD226
ImmunogenTh1 polarized T cell clones
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD226 (DNAM-1) is constitutively expressed on native CD8+cells and on CD4+T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4+cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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