Purified anti-mouse CD90 Antibody anti-CD90 - G7,BioLegend,105202
Clone G7 binds to Thy-1 epitope region A and also recognizes Thy-1.1/CD90.1 and Thy-1.2/CD90.2 alloantigens. Additional reported applications (for the relevant formats) include:in vitroT-cell activation1,3-4,6, induction of apoptosis2,5, and immunohistochemical staining7,8of zinc-fixed paraffin-embedded sections and acetone-fixed frozen sections. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 105204).
Host
Rat
Reactivity
Mouse
Application
FC -Quality testedIHC-F -Verified
Platform ID
BAB223904412
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
CD90 is a 25-35 kD immunoglobulin superfamily member, also known as Thy-1. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells, but not on B cells. CD90 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90 is involved in costimulation of lymphocyte proliferation and activation, and hematopoietic stem cell differentiation. CD90 has been shown to interact with CD45. The G7 antibody is able to stimulate T cell proliferation and IL-2 secretion and induce apoptosis of thymocytes and CTL clones.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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