Purified anti-mouse Jagged 2 Antibody anti-Jagged 2 - HMJ2-1,BioLegend,131001
Host
Armenian Hamster
Reactivity
Mouse
Application
FC - Quality testedIHC - Reported in the literature, not verified in house
Platform ID
BAB111136038
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePurified anti-mouse Jagged 2 Antibody anti-Jagged 2 - HMJ2-1
Cat. No.131001
HostArmenian Hamster
RRIDAB_1227682 (BioLegend Cat. No. 131001)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality testedIHC - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberHMJ2-1
Concentration0.5 mg/ml
TargetJagged 2
ImmunogenCHO cells expressing murine Jagged-2
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
The Notch receptors and their ligands are highly conserved from invertebrates to mammals. The Jagged-2 is one of the several Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus. This translocation triggers a series of signaling process. Jagged-2 is reported to be essential for the regulation of spermatogenesis.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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