Purified anti-mouse Ki-67 Recombinant Antibody, Ki-67, QA18A32,BioLegend,163202

Host

Rat

Reactivity

Mouse

Application

IHC-F - Quality testedICC - Verified

Platform ID

BAB688348958

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-mouse Ki-67 Recombinant Antibody, Ki-67, QA18A32
Cat. No.163202
HostRat
RRIDAB_2904309 (BioLegend Cat. No. 163202)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationIHC-F - Quality testedICC - Verified
ClonalityRecombinant
Clone NumberQA18A32
Concentration0.5 mg/mL
TargetKi-67
ImmunogenE. coli expressed, N-terminal His-Thioredoxin-tagged, partial mKi-67 (1816-2163 aa) recombinant protein.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase. While in G0 phase, the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.

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