Purified anti-mouse/rat CD62E E-selectin Antibody anti-CD62E - RME-1/CD62E,BioLegend,148801

Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5, Western blotting1, immunoprecipitation1, ELISA7, and blocking1,2,3. Forin vivostudies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 148803).

Host

Mouse

Reactivity

Mouse, Rat

Application

ICC -Quality testedIHC-F -VerifiedWB, IP, ELISA, Block -Reported in the literature, not verified in house

Platform ID

BAB461124285

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-mouse/rat CD62E E-selectin Antibody anti-CD62E - RME-1/CD62E
Cat. No.148801
HostMouse
RRIDAB_2564222 (BioLegend Cat. No. 148801)AB_2564223 (BioLegend Cat. No. 148802)
IsotypeMouse IgG1, κ
ReactivityMouse, Rat
ApplicationICC -Quality testedIHC-F -VerifiedWB, IP, ELISA, Block -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberRME-1/CD62E
Concentration0.5 mg/mL
TargetCD62E
ImmunogenRat E-selectin transfected chinese hamster ovary cells
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

CD62E (also known as E-selectin, ELAM-1, and LECAM-1) is a 115 kD type I transmembrane protein and a member of the selectin family. CD62E is highly expressed on activated endothelial cells. CD62E is involved in leukocyte tethering and rolling on activated endothelium at inflammatory sites and may also play a role in tumor metastasis and angiogenesis. CD62E binds to both Sialyl Lewis X (CD15s) and PSGL-1 (CD162).

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