Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody,Abbexa,abx000875

PDK1 Antibody is a Rabbit Polyclonal antibody against PDK1. PDK1(pyruvate dehydrogenase kinase isoform 1) is also named as PDHK1 and belongs to the PDK/BCKDK protein kinase family.It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism(PMID:17683942).Starvation increases islet PDK activity(PMID:11723055).This antibody is speicfic to PDK1.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC

Conjugate

Unconjugated

Platform ID

BAB059129979

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NamePyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody
Cat. No.abx000875
Accession NumberQ15118
Gene ID (Entrez)5163
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC
Working DilutionsWB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration1 mg/ml
Molecular WeightCalculated MW: 49 kDa/51 kDa Observed MW: 49 kDa
TargetPDK1
ImmunogenA synthetic peptide corresponding to human PDK1/PDHK1
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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