Pyruvate dehydrogenase kinase 1 / PDK1 antibody [4A11],Genetex,GTX60386

Host

Mouse

Reactivity

Human, Mouse, Rat, Monkey

Application

WB ICC/IF IHC-P FCM ELISA

Conjugate

Unconjugated

Platform ID

BAB890230859

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePyruvate dehydrogenase kinase 1 / PDK1 antibody [4A11]
Cat. No.GTX60386
Gene ID (Entrez)5163
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM ELISA
ClonalityMonoclonal
TargetPDK1
ImmunogenPurified recombinant fragment of human PDK1 expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

Synonyms

pyruvate dehydrogenase kinase 1

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