RAB3D Antibody,StressMarq Biosciences Inc.,SMC-614D

Mouse Anti-Human RAB3D Monoclonal IgG1

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB

Conjugate

APC, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC, HRP, PerCP, RPE, Unconjugated

Platform ID

BAB464276334

StressMarq Biosciences Inc.

Headquarters

118-1537 Hillside Avenue, Victoria, British Columbia, V8T 4Y2, CANADA

Contact

Tel: +1 250-294-9065
Fax: +1 250-294-9025

Product Specifications
Scientific Background
Synonyms

Specifications

NameRAB3D Antibody
Cat. No.SMC-614D
Accession NumberO95716
Gene ID (Entrez)9545
HostMouse
RRIDAB_3716681)
ReactivityHuman, Mouse, Rat
ConjugationAPC, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC, HRP, PerCP, RPE, Unconjugated
ApplicationWB
Working DilutionsWB (1:1000); optimal dilutions for assays should be determined by the user.
ClonalityMonoclonal
Concentration1mg/mL
ImmunogenFull length recombinant Human RAB3D protein
PurityProtein G Purified
ShippingBlue Ice or 4ºC
FormulationPBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
Storage-20ºC, Conjugated antibodies should be stored according to the product label

Scientific Background

RAB3D is a member of the Rab family of small GTPases involved in regulated exocytosis. It plays a role in vesicle trafficking from the trans-Golgi network and is essential for protein secretion in various cell types. Although best known for its function in osteoclast-mediated bone resorption, RAB3D is also expressed in the nervous system, where it may influence synaptic vesicle dynamics and neurotransmitter release. Given the importance of vesicle trafficking in neuronal communication, dysregulation of RAB3D could contribute to synaptic dysfunction in neurodegenerative diseases. Its role in exocytosis makes it a candidate for further investigation in disorders characterized by impaired synaptic transmission.

Synonyms

Member RAS Oncogene Family, D2-2, GOV, RAB16, RAD3D, Ras-Related Protein Rab-3D

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